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Canadian teen discovers cystic fibrosis breakthrough

A 16-year-old from Toronto is the latest wunderkind to prove that however lofty your life goals may be, somewhere, a teenager has already achieved them. Marshall Zhang, a student at Richmond Hill's Bayview Secondary School, may have created a new drug cocktail that will help fight cystic fibrosis, a progressive, fatal genetic disease that eventually results in difficulty digesting food and breathing.
By Vanessa Milne
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Canadian teen discovers cystic fibrosis breakthrough Getty Images

A 16-year-old from Toronto is the latest wunderkind to prove that however lofty your life goals may be, somewhere, a teenager has already achieved them.

Marshall Zhang, a student at Richmond Hill's Bayview Secondary School, may have created a new drug cocktail that will help fight cystic fibrosis, a progressive, fatal genetic disease that eventually results in difficulty digesting food and breathing.

With the help of a mentor, Zhang used a supercomputer to run virtual drug docking - creating computer simulations of how a drug works — to look into how two new compounds fight cystic fibrosis.

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He discovered that they acted on different spots — which meant that they could probably be used together. Then he tested them in combination, and found the results even better than he was expecting.

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The research, which he did for the Sanofi-Aventis BioTalent Challenge, won him first prize — and international media attention. He doesn't seem to be letting it get to his head though: On May 12, he tweeted "wow. the stories i'm hearing from around the world about families and their struggles with CF are truly inspirational. all the best."

His mentor, Christine Bear, a researcher at the Hospital for Sick Children in Toronto, has invited him back during the summer to continue his research.

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"They actually worked together in creating an effect that was greater than the sum of its parts," she told LiveScience.

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